Intestinal screening

We recommend intestinal screening for all patients with subsequent problems. An intestinal screening in conjunction with the SKB blood test provides further information and is therefore also recommended.

• Determination of the quantity and quality of the intestinal biota (microbiome) and mucosal immunity
• Presence of inflammation
• Dysbiosis and food allergies
• Immune system assessment
• Digestive problems / gastrointestinal problems
• Chronic inflammation (uluerosa colitis, Chron’s disease, etc.)
• Colon irretable (irritable bowel syndrome)
• Stool irregularities such as diarrhea/constipation
• Skin rashes and dermatoses
• Liver overload and increased liver values in the blood count
• Allergies
• Histamine intolerance
• Lactose intolerance
• Gluten intolerance
• Food intolerances
• Stress, born out, depression
• Increased susceptibility to infection (often sick)
• Exposure to microorganisms: fungi, parasites, bacteria, viruses
• All forms of autoimmune diseases
• Condition after intestine – operation, for example partial resection of sections of intestine.

The “Basic Intestinal Examination” is a very extensive examination package consisting of several examinations:

Provides a guideline for digestive absorption and digestive disorders

The pH value of the stool says a lot about the state of the microbiome and our nutritional behavior. Here’s what you can do if your stool pH is too high or too low.

The pH value in the colon should be slightly acidic, because then the intestinal bacteria feel most comfortable. A healthy stool pH is 5.5 to 6.5. In our usual Central European diet, the pH value often rises to values between 6 and 7 or even higher.

A slightly acidic colon pH is not only important for healthy intestinal flora. It also prevents foreign, potentially pathogenic bacteria from multiplying in the intestines. As a result, an acidic pH value also suppresses microbial putrefactive processes, which often lead to flatulence and other intestinal problems.

The human colon contains 10¹¹ bacteria per gram, making it the largest bacterial population in the body. Most of them are anaerobic.

The resident intestinal microbiota consists of intestinal bacteria that are essential for the physiological processes in the intestine. Its exact composition develops in the first years of life and is as personal as a fingerprint.

The transient gut microbiota, also known as passing gut microbiota, is absorbed through food. It consists of bacteria that are tolerated to some extent, but they are generally useless and some are pathogenic.

The resident gut microbiota consists of the following bacteria:

• Anaerobic bacteria: Bacteroid species, Bifidobacterium species
• Aerobic bacteria: Escherichia coli, enterococcal species
• Micro-aerophilic bacteria: Lactobacillus species

Determines “fungal parameters in the intestine”
Is there a disruption of the microbiome caused by fungi.

Determines “virulent parameters in the intestine”
Is there a disruption of the microbiome caused by viruses.

The main function of IgA is to protect the body from the invasion of all kinds of pathogens due to its presence in tears, colostrum, bile and the glands of the respiratory, urinary and gastrointestinal tracts. sIgA provides clarity about the quality of the gut-associated immune system.

An abnormal result, too much or too little secretory IgA, indicates that the intestinal immune system is not functioning properly.

An antimicrobial peptide. It is produced endogenously by neutrophil granulocytes and is part of the innate immune system (first-line defense). It provides insight into the activity of non-specific mucosal immunity

Detection of intestinal infections, leaky gut syndrome and food intolerances.

Alpha-1-antitrypsin (α-1-antitrypsin) is an anti-inflammatory agent produced in liver and intestinal cells. The liver produces 2 grams per day.

It is an acute phase protein that, among other things, inhibits inflammatory enzymes and has an antiproteolytic effect. For example, α-1-antitrypsin inhibits the action of the enzyme elastase. Elastase breaks down elastin, an important part of connective tissue. Alpha-1 antitrypsin is measured in feces and is ideal for very early detection of inflammation.

Note: Alpha 1-antitrypsin increases over time as inflammation increases. However, α-1 antitrypsin decreases when inflammation increases further than α-1 antitrypsin can control. The analytical value should therefore always be evaluated in addition to inflammatory values such as calprotectin, PMN elastase, lysozyme, hsCRP and lactorferrin.

• EPX (eosinophil protein X)

One of the four largest proteins found in the granules of human eosinophilic leukocytes (granulocytes). They play a key role in the allergic inflammatory process. EPX is used as a parameter in stool to detect inflammation and atopic eczema due to allergies and/or food intolerances, to measure the activity of the present inflammation and to test the effectiveness of an elimination diet. Experience has shown that EPX also reacts to parasitic infections.

Calprotectin, lactoferrin, hemoglobin and transferrin.

The human organism reacts with an inflammatory reaction to attacks by invading pathogens (microorganisms and viruses) or damaged tissue (after accidents or operations).

This qualitative inflammatory screening determines the presence of the inflammatory parameters calprotectin, lactoferrin, hemoglobin and transferrin.

The parameters calprotectin and lactoferrin are useful for distinguishing between functional (e.g. irritable bowel syndrome) and organic diseases (e.g. chronic intestinal inflammation). Gastrointestinal inflammatory diseases include Crohn’s disease and ulcerative colitis. This may be highly suspected in patients with persistent (≥4 weeks) or recurrent (≥2 events per 6 months) abdominal pain or diarrhea. The presence of rectal bleeding, weight loss, or anemia increases the likelihood of the disease. Endoscopic examination with histopathological sampling is often indispensable for the diagnosis.

Interested? Arrange a consultation appointment for stool analysis today.

Your NMC team Krk